Click on an interpretive center below to verify its active status. ICs that are complete are indicated by the word “Active”.
Interpretive Centers
- Arkansas Post Museum State Park
- Black Hawk State Historic Site
- Buffalo Bill Museum and Lone Star Steamer
- Cahokia Mounds State Historic Site
- Cairo Custom House Museum
- Cape Girardeau Conservation Campus Nature Center
- Charles Lindbergh House and Museum - Active
- Chucalissa and the C.H. Nash Museum
- Columbus-Belmont State Park
- Dale Bumpers White River National Wildlife Refuge Visitor Center
- Delta Blues Museum - Active
- Delta Cultural Center
- Delta Gateway Museum - Active
- Des Moines County Heritage Museum
- Discovery Park of America
- Driftless Area Education and Visitor Center
- EB Lyons Interpretive Center at Mines of Spain
- Effigy Mounds National Monument
- Environmental Learning Center – Muscatine - Active
- Forest History Center - Active
- Fort Crawford Museum
- Fort de Chartres State Historic Site
- Gateway Arch National Park
- Genoa National Fish Hatchery and Great River Road Interpretive Center
- George M. Verity Riverboat Museum
- Grand Gulf Military Monument Commission, aka Grand Gulf Park
- Great River Road Visitor and Learning Center
- Hampson Archeological Museum State Park
- Helena Museum of Phillips County
- Historic Dyess Colony: Johnny Cash Boyhood Home
- Historic Fort Snelling - Active
- Hurstville Interpretive Center
- Iowa Department of Natural Resources Fish Aquarium
- Itasca County Historical Society - Active
- Itasca State Park – Jacob V. Brower Visitor Center - Active
- Jean Lafitte National Historical Park & Preserve
- Lake Chicot State Park
- Lakeport Plantation
- Louisiana State Museum
- Lower Mississippi River Museum
- LSU Rural Life Museum & Windrush Gardens
- Mark Twain Boyhood Home and Museum
- Mill City Museum - Active
- Minnesota History Center - Active
- Minnesota Marine Art Museum - Active
- Mississippi County Museum
- Mississippi River State Park Visitor Center
- Mississippi River Visitor Center Locks and Dam 15 - Active
- Mississippi Welcome Center/Woodville Hospitality Station
- Motor Mill Historic Site
- Museum of the Arkansas Grand Prairie
- Nahant Marsh Education Center
- Natchez Convention and Visitor Bureau
- National Eagle Center - Active
- National Great Rivers Museum
- National Mississippi River Museum & Aquarium
- New Madrid Historical Museum
- NPS Mississippi River Visitor Center - Active
- Old Fort Madison
- Oliver Kelley Farm - Active
- Parkin Archeological State Park
- Pere Marquette State Park
- Pierre Menard Home and Fort Kaskaskia State Historic Sites
- Pine Creek Grist Mill
- Plaquemine Lock State Historic Site
- Port Hudson State Historic Site
- Poverty Point UNESCO World Heritage Site
- Putnam Museum and Science Center
- Reelfoot Lake State Park
- Science Museum of Minnesota
- Sikeston Depot Museum
- Ste. Genevieve Welcome Center
- Stonefield Historic Site
- Sultana Disaster Museum
- The Historic New Orleans Collection
- The Louisiana Great River Road Interpretive Center and Museum
- The National Pearl Button Museum - Active
- The Potosi Brewing Company
- The Sawmill Museum
- Toolesboro Mounds National Historic Landmark - Active
- Trail of Tears State Park
- Tunica RiverPark Museum
- Upper Mississippi River National Wildlife and Fish Refuge Visitor Center
- Vicksburg National Military Park
- Villa Kathrine
- Villa Louis
- Washington County Welcome Center & Museum of the Delta/River Road Queen Welcome Center
- West Feliciana Historical Society Museum
- Wickliffe Mounds State Historic Site
- Winona County History Center - Active
- WWII Japanese American Internment Museum