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State: Missouri

Sikeston Depot Museum

Learn about the history and industry of the Mississippi River region at this charming museum and former train depot, located in southeast Missouri. Visitors will find exhibits about the Mississippian Indian tribe, Sikeston’s cotton-growing heritage and local history, as well as works from local artists. Be sure to check out the reconstructed red caboose, a local landmark.

Interpretive Center Contact Info

Contact Person Contact Info

  • Name
  • Address
    116 West Malone Avenue
  • City
  • State
  • Zip
  • Phone
    (573) 481-9967
  • Email

Interpretive Center Status

  • Name
  • Email
  • Date

National Office Contact Information


National MRPC Office
PO Box 7395
Madison, WI 53707-7395


Toll Free: 866-763-8310
E-mail: [email protected]